OBAGI Medical Retinol + PHA Refining Night Cream 50ml

OBAGI Medical Retinol + PHA Refining Night Cream is an advanced overnight treatment designed to refine skin texture and tone while reducing the appearance of blemishes, fine lines, and wrinkles. In as little as 4 weeks, skin appears smoother, clearer, and more even-looking.

Formulated with Entrapped Retinol powered by slow-release technology, this cream delivers optimised retinol release into deeper layers of the skin to encourage cell turnover while helping minimise irritation. Polyhydroxy Acid (Gluconolactone) provides gentle surface exfoliation, while nourishing ingredients help maintain hydration and barrier support for balanced, resilient skin.

Clinically proven results are based on a 2024 to 2025 8-week clinical test. Data on file at Obagi Cosmeceuticals LLC.

Key Information

• Works overnight to refine texture and tone

• Helps reduce the appearance of blemishes, fine lines, and wrinkles

• Slow-release Entrapped Retinol for optimised delivery

• Polyhydroxy Acid for gentle exfoliation

• Formulated with hydrating and barrier-supporting ingredients

• Suitable for normal, dry, oily, and combination skin

Backed by Clinical Trials

• 90% showed visible improvement in smoothness in 4 weeks

• 90% noticed reduced appearance of blemishes in 4 weeks

• 87% reported more even-looking skin tone in 8 weeks

• 80% noticed softened appearance of fine lines in 8 weeks

Additionally clinically proven to:

• Improve skin smoothness by 29%

• Improve skin tone evenness by 10%

• Be well tolerated by the skin

Key Ingredients

Entrapped Retinol
A gold-standard Vitamin A derivative delivered through innovative slow-release microsphere technology to enhance stability, encourage cell turnover, and minimise irritation.

Polyhydroxy Acid (Gluconolactone)
A gentle exfoliating acid that smooths texture, improves tone, and supports hydration.

Sodium Hyaluronate
A humectant with intense hydration capabilities.

Vitamin E (Tocopherol)
An antioxidant that helps protect against oxidative stress while nourishing the skin.

Squalane
Supports hydration and strengthens the skin barrier by mimicking natural sebum.

Glycerin
A powerful humectant that supports the skin’s moisture barrier.

Hydrogenated Lecithin
Helps maintain hydration by mimicking natural skin lipids.

Shea Butter
A nourishing emollient rich in vitamins A and E that helps seal in moisture.

How To Use

Apply to face in the evening.
Apply sunscreen before sun exposure.

Storage

Store at controlled room temperature between 15°C and 25°C (59°F to 77°F).
Keep out of direct sunlight.

Safety Information

When using this product keep out of eyes. If contact occurs, rinse thoroughly with water.
For external use only.
Keep out of reach of children.
It is recommended that prior to sun exposure, areas where AHAs have been applied are protected with sunscreen.
Contains Vitamin A. Consider your daily intake before use.

Full Ingredients

Aqua/Water/Eau, Caprylic/Capric Triglyceride, Gluconolactone, Glycerin, Cetearyl Alcohol, Helianthus Annuus (Sunflower) Seed Oil, Cetyl Alcohol, Cetyl Esters, Sodium Hydroxide, Dimethicone, Hydrogenated Lecithin, Butyrospermum Parkii (Shea) Butter Extract, Retinol, Sodium Hyaluronate, Cetearyl Glucoside, Jojoba Esters, Tocopherol, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 20, Ethylhexylglycerin, Squalane, Carbomer, Allyl Methacrylates Crosspolymer, Xanthan Gum, Phenoxyethanol, Tetrasodium Glutamate Diacetate, Polysorbate 60, Sorbitan Isostearate, Citric Acid.